Ipamorelin
Ipamorelin is a pentapeptide consisting of five amino acids. It functions as a GH secretagogue, acting as an agonist that binds to specific cell receptors and triggers cellular responses. In animal studies, Ipamorelin has been shown to stimulate the pituitary gland, enhancing the secretion of growth-related substances while simultaneously inhibiting somatostatin, a hormone that suppresses growth. Additionally, Ipamorelin promotes the production of Insulin-like Growth Factor 1 (IGF-1), which plays a crucial role in the growth and repair of muscle and skeletal tissues.
Product Usage
This product is intended for research purposes only. It is strictly designated for in vitro testing and laboratory experimentation. All information provided on this website is for educational purposes only. Any introduction into humans or animals is strictly prohibited by law. Only licensed, qualified professionals should handle this product. It is not a drug, food, or cosmetic and must not be misbranded, misused, or mislabeled as such.
Introduction to Ipamorelin
Ipamorelin is emerging as a noteworthy growth hormone secretagogue. Scientific research suggests that it has significant potential in stimulating growth hormone production. This peptide may offer a wide range of potential benefits.
Structure
Sequence: Aib-His-D-2-Nal-D-Phe-Lys-NH2
Molecular Formula: C38H49N9O5
Molecular Weigh: 711.85 g/mol
Research on Ipamorelin
Part 1: Overview and Mechanism of Action
Ipamorelin is a distinctive pentapeptide derived from GHRP-1, recognized for its ability to selectively stimulate growth hormone (GH) release while minimally affecting other hormone levels.
Part 2: Pharmacological Studies on Ipamorelin
Extensive research has explored Ipamorelin’s pharmacological properties, providing valuable insights into its effects on the body.
Key findings include:
- Significant increases in cortical bone mineral content (BMC).
- Expansion of femur and vertebra L6 volumes.
- Increased body weight, cortical bone area, and BMC.
- Notable improvements in dry defatted weight and bone volume after 12 weeks.
Ipamorelin’s Impact on Longitudinal Bone Growth in Rats
Studies indicate that Ipamorelin enhances longitudinal bone growth rate (LGR) and body weight (BW) in rats.
Additional findings:
- A shorter median time to the first tolerated meal in the Ipamorelin group.
- Comparable safety and efficacy profiles between Ipamorelin and placebo groups.
Potential Side Effects
While generally well-tolerated, Ipamorelin may cause:
- Fluid retention
- Joint pain
- Headaches
- Increased appetite
- Altered insulin response, potentially affecting blood sugar levels.
Ipamorelin is a growth hormone secretagogue known for its selective action and potential benefits in promoting bone growth and managing postoperative ileus. Although some side effects have been observed, further in-depth research is required to fully assess its safety and effectiveness.
DISCLAIMER: FOR INFORMATIONAL AND EDUCATIONAL PURPOSES ONLY
All articles and product details provided on this website are strictly for informational and educational purposes.
The product information presented here applies solely to in-vitro studies—experiments conducted outside of living organisms, such as in laboratory settings. These products are not classified as medicines or drugs and have not been approved by the FDA for the prevention, treatment, or cure of any medical conditions, ailments, or diseases.
Furthermore, the use of these products in humans or animals is strictly prohibited by law.
